Macroscopic identification of early myocardial infarction by dehydrogenase alterations

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Macroscopic identification of early myocardial infarction by dehydrogenase alterations.

A method utilizing a general dehydrogenase reaction has been used to demonstrate early gross myocardial infarctions. The procedure takes advantage of substrate and enzyme loss from the damaged myocardium. In the viable muscle, where endogenous substrates, coenzymes, and dehydrogenases are present, reduction of Nitro-BT yields a dark blue formazan. Necrotic muscle fibres remain unstained by this...

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Serum Lactic Dehydrogenase Estimations in Myocardial Infarction.

The clinical features presented by coronary occlusion with myocardial infarction are such that, together with electrocardiographic evidence, a correct diagnosis is usually possible (Price, 1950). Electrocardiographic changes, however, may sometimes be delayed, and in about 6 per cent of cases no change is detectable at all (Lancet, 1958). To assist in diagnosing these cases, enzyme tests have b...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1966

ISSN: 0021-9746

DOI: 10.1136/jcp.19.5.479